Stanford Study Finds Vaccine mRNA and Spike Protein Persist in the Body for Months Following Vaccination – But Not Following Infection
By Will Jones | The Daily Sceptic | March 18, 2022
A study from Stanford University, published in Cell, has found that vaccine mRNA and spike protein persist in lymph nodes for up to two months following the second vaccine dose. This is in contrast to what happens following infection, where spike protein was found only rarely.
In contrast to disrupted germinal centres in lymph nodes during infection, mRNA vaccination stimulates robust germinal centres containing vaccine mRNA and spike antigen up to eight weeks postvaccination in some cases…
The observed extended presence of vaccine mRNA and spike protein in vaccinee lymph node germinal centres for up to two months after vaccination was in contrast to rare foci of viral spike protein in COVID-19 patient lymph nodes… COVID-19 patient lymph nodes showed lower quantities of spike antigen.
The researchers also found the concentration of spike protein in the blood following vaccination was similar to that during infection.
At least some portion of spike antigen generated after administration of BNT162b2 becomes distributed into the blood. We detected spike antigen in 96% of vaccinees in plasma collected one to two days after the prime injection, with antigen levels reaching as high as 174 pg/mL. The range of spike antigen concentrations in the blood of vaccinees at this early time point largely overlaps with the range of spike antigen concentrations reported in plasma in a study of acute infection, although a small number of infected individuals had higher concentrations in the ng/mL range. At later time points after vaccination, the concentrations of spike antigen in blood quickly decrease although spike is still detectable in plasma in 63% of vaccinees one week after the first dose.
The researchers found evidence of ‘original antigenic sin’ from the vaccines, where a person vaccinated and then infected with a variant develops a weaker antibody response to that variant than an unvaccinated person infected with the variant. They describe it as a “strong imprinting effect of prior vaccination”.
We find that prior vaccination with Wuhan-Hu-1-like antigens followed by infection with Alpha or Delta variants gives rise to plasma antibody responses with apparent Wuhan-Hu-1-specific imprinting manifesting as relatively decreased responses to the variant virus epitopes, compared with unvaccinated patients infected with those variant viruses…
The extent to which vaccine boosting or infection with different variants will effectively elicit antibody responses to new epitopes or rather increase responses to the epitopes of antigens encountered previously, as in the ‘original antigenic sin’ phenomenon described for influenza virus infection and vaccination, will be an important topic of ongoing study.
The researchers confirmed the fast decline of antibodies following vaccination, finding a 20-fold drop after nine months.
Our data demonstrate that vaccinee plasma and saliva spike and receptor-binding domain-specific IgG concentrations decrease from their peak values by approximately 20-fold by nine months after primary vaccination but quickly exceed prior peak concentrations in seven to eight days after boosting with a third vaccine dose.
The study also confirms that vaccination doesn’t generate IgA antibodies (found especially in the respiratory and digestive tracts and mounting a first defence against infection) or IgM antibodies (found especially in the blood and lymph fluid), but only IgG antibodies (found in the blood). This has been proposed as a reason that vaccination is so poor at preventing infection and transmission.
Surprisingly, perhaps, the researchers found that vaccination (whether mRNA, adenoviral or inactivated virus) stimulated a broader antibody (IgG) response than infection, leading them to predict that “antibodies derived from infection may provide somewhat decreased protection against virus variants compared with comparable concentrations of antibodies stimulated by vaccination”.
However, the post-infection IgG antibody response improved over several weeks.
Over time, infected patient plasma samples showed improvement in variant receptor-binding domain binding relative to Wuhan-Hu-1 receptor-binding domain, suggesting evolution of the antibody response through at least seven weeks post-onset of symptoms.
In addition, the apparent breadth-benefit of vaccination over infection disappeared when “whole spike antigens” were tested rather than just the receptor-binding domain targeted by the vaccine, suggesting the benefit may be an artefact of the study design not found in a real encounter with the virus.
Notably, the increased breadth of vaccinee IgG compared with COVID-19 patient IgG binding to viral variant antigens was greatest for receptor-binding domain, the main target of neutralising antibodies, and was decreased or not detected when whole spike antigens were tested.
Other limitations mentioned include not looking at “antibodies binding to the spike N-terminal domain” or other antibodies: “Our data do not reflect potentially functional antibodies binding to the spike N-terminal domain, or antibodies that may have other activities in vivo.”
The study also didn’t look at T cell responses, among other things:
Further mechanistic investigations into the differences in antibody breadth elicited by vaccination and infection are needed to define the roles of T cell help, antibody affinity maturation, germinal centre function, and innate immune responses to vaccine components, as well as the cellular and subcellular distribution of vaccine RNA and expressed antigen in lymphoid tissues.
The high concentration in the blood of spike protein following vaccination and its persistence along with vaccine mRNA in lymph nodes for months, in contrast to the situation post-infection where such persistence is rare, will fuel concerns about the safety of these Covid vaccines. It has been argued that the spike protein is itself pathogenic, not inert, and that the free spike proteins generated by the vaccines have greater capacity to bind to more types of cells than the virus particles themselves, and that this may be what lies behind many of the serious adverse events reported to regulatory bodies and identified in case reports. This warrants further investigation.
Share this:
Related
March 19, 2022 - Posted by aletho | Science and Pseudo-Science, Timeless or most popular | COVID-19 Vaccine
2 Comments »
Leave a comment Cancel reply
This site uses Akismet to reduce spam. Learn how your comment data is processed.
Featured Video
PEDIATRIC-PERSPECTIVES—MEASLES-OUTBREAK-BREAKDOWN
or go to
Aletho News Archives – Video-Images
From the Archives
SAN BERNARDINO IN FLUX: The Fluid Nature of Cover Stories
By Niles and Frasier Mercado • Memory Hole • December 22, 2015
If the reporting on the alleged shooting in San Bernardino, California has left you confused and disoriented, you are not alone. The main stream media has changed substantial aspects of their original official story.
While it is understandable that some details might get misreported in the immediate aftermath of a national tragedy, no mention is made as to WHERE this misinformation originated from and WHY we should think that the NEW news reports are any more reliable.
It is difficult to dispute or verify claims when the narrative is a moving target. These evolving details are pretty significant, and seem to be — along with crisis actors and concurrent drills — another fingerprint of government sponsored shooting hoaxes and false flag events. Let’s take a look at a few of these alterations and how they relate to inconsistencies in other government-sponsored events. … continue
Blog Roll
-
Join 2,756 other subscribers
Visits Since December 2009
- 6,741,806 hits
Looking for something?
Archives
Calendar
Categories
Aletho News Civil Liberties Corruption Deception Economics Environmentalism Ethnic Cleansing, Racism, Zionism Fake News False Flag Terrorism Full Spectrum Dominance Illegal Occupation Mainstream Media, Warmongering Malthusian Ideology, Phony Scarcity Militarism Progressive Hypocrite Russophobia Science and Pseudo-Science Solidarity and Activism Subjugation - Torture Supremacism, Social Darwinism Timeless or most popular Video War Crimes Wars for IsraelTags
9/11 Afghanistan Africa al-Qaeda Australia BBC Benjamin Netanyahu Brazil Canada CDC Central Intelligence Agency China CIA CNN Colombia Covid-19 COVID-19 Vaccine Da’esh Donald Trump Egypt European Union Facebook FBI FDA France Gaza Germany Google Hamas Hebron Hezbollah Hillary Clinton Human rights India Iran Iraq ISIS Israel Israeli settlement Japan Jerusalem Joe Biden Korea Latin America Lebanon Libya Middle East National Security Agency NATO New York Times North Korea NSA Obama Pakistan Palestine Qatar Russia Sanctions against Iran Saudi Arabia Syria The Guardian Turkey Twitter UAE UK Ukraine United Nations United States USA Venezuela Washington Post West Bank WHO Yemen ZionismRecent Comments
5 dancing shlomos on West Confirms Its Intention to… 5 dancing shlomos on ICC MUST INVESTIGATE BRITISH M… Mooseings on Israel carries out ethnic clea… roberthstiver on Stop taking advantage of Ukrai… 5 dancing shlomos on Japan’s most senior cancer doc… 5 dancing shlomos on ICC applies for arrest warrant… roberthstiver on Israeli officials’ jaws… papasha408 on Georgian President Vetoes Fore… poisonedwater on Washington is essentially defy… poisonedwater on Houthis Take Down Another US R… poisonedwater on Israeli officials’ jaws… Dennis Wilson on Labor strike in 10 California…
Aletho News
- The Media Slowly Backpedals
- Itamar Ben-Gvir promotes future Israeli settlements in Gaza
- Report: Israel systematically abuses jailed Palestinian leader Marwan Barghouti
- Washington has ‘no objections’ to Israel’s brutal assault on Rafah
- ICC MUST INVESTIGATE BRITISH MINISTERS FOR COMPLICITY IN GAZA WAR CRIMES
- Possible Broader Plot Behind Slovak Premier’s Shooting
- PEDIATRIC-PERSPECTIVES—MEASLES-OUTBREAK-BREAKDOWN
- West Confirms Its Intention to Militarize Space – Nebenzia
- A Global Censorship Prison Built by the Women of the CIA
- American Pravda: Rosencrantz and Guildenstern Are Dead in San Bernardino
If Americans Knew
- Israel shuts down Associated Press’ Gaza live video feed, confiscates equipment
- NYC deputy mayor charges Washington Post with antisemitism
- The Right of Return to Free Palestine
- Netanyahu calls ICC arrest applications “the new antisemitism” – Day 227
- Unpacking the Israeli campaign to deny the Gaza genocide
- Billionaires for Israel started a group with 100 members to secretly work on behalf of Israel
- Why Did the US Spend $320 Million on a Rube Goldberg Pier For Gaza?
- The State Department Says Israel Isn’t Blocking Aid. Videos Show The Opposite.
- War on Gaza: Why Israel deserves to be singled out for criticism
- Medical Workers Evacuated from Gaza, But 3 Americans Refuse To Leave
Richie Allen
- The Richie Allen Show Returns Tomorrow Wednesday April 24th
- Call Richie Today Monday March 11th From 4.30pm
- Connect To The Richie Allen Show WhatsApp Today
- NHS Asks Patients To Choose From 12 Genders, 10 sexual Preferences & 159 Religions
- The Richie Allen Show Moves To A New Time Slot From Monday Nov 20th
- Starmer Will Sack Shadow Ministers Who Vote For Gaza Ceasefire
- AI Tool Can Predict Heart Attacks Years In Advance
- Nepal Bans TikTok To Preserve Social Harmony
- Bloke Appointed Boss Of Womb Health Charity
- WHO – “Gaza’s Biggest Hospital Becoming A Cemetery”
No Tricks Zone
- Climate Research Paper Finds Tropical Storm Variability Linked Mostly To Oceanic Cycles
- HadCRUT Has Now Fully Removed 0.15°C From The 1940s Warmth ‘Blip’ As Proposed In 2009 E-mails
- Data Reveal That US Heat Wave Index, Japan Drought Coincide With Solar Activity
- New Study Finds An Extremely Low CO2 Climate Sensitivity For The Arctic And Antarctic
- U.N. Contributing Scientist: ‘Culling’ Human Population Could Avert Climate Catastrophe
- Using Nets On The Seafloor To Retrieve Seafood ‘Roughly The Same As Running 100 Coal-Fired Plants’
- New Paper: Global Warming Leading To HIMALAYAN COOLING, Preventing Glacial Melt!
- DNA Evidence Reveals Domestic Cats, Dogs, African Wildcats, Frogs Lived In The Arctic 9000 Years Ago
- -80°C: Antarctic Vostok Station Records “Extreme Winter Cold”…Not Even Winter Yet!
- The German E-Vehicle Nightmare, 2024 Q1 Sales Plummet 14%… “Graveyard” For Unsold Cars
More Links
Contact:
atheonews (at) gmail.com
Disclaimer
This site is provided as a research and reference tool. Although we make every reasonable effort to ensure that the information and data provided at this site are useful, accurate, and current, we cannot guarantee that the information and data provided here will be error-free. By using this site, you assume all responsibility for and risk arising from your use of and reliance upon the contents of this site.
This site and the information available through it do not, and are not intended to constitute legal advice. Should you require legal advice, you should consult your own attorney.
Nothing within this site or linked to by this site constitutes investment advice or medical advice.
Materials accessible from or added to this site by third parties, such as comments posted, are strictly the responsibility of the third party who added such materials or made them accessible and we neither endorse nor undertake to control, monitor, edit or assume responsibility for any such third-party material.
The posting of stories, commentaries, reports, documents and links (embedded or otherwise) on this site does not in any way, shape or form, implied or otherwise, necessarily express or suggest endorsement or support of any of such posted material or parts therein.
The word “alleged” is deemed to occur before the word “fraud.” Since the rule of law still applies. To peasants, at least.
Fair Use
This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a ‘fair use’ of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more info go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond ‘fair use’, you must obtain permission from the copyright owner.
DMCA Contact
This is information for anyone that wishes to challenge our “fair use” of copyrighted material.
If you are a legal copyright holder or a designated agent for such and you believe that content residing on or accessible through our website infringes a copyright and falls outside the boundaries of “Fair Use”, please send a notice of infringement by contacting atheonews@gmail.com.
We will respond and take necessary action immediately.
If notice is given of an alleged copyright violation we will act expeditiously to remove or disable access to the material(s) in question.
All 3rd party material posted on this website is copyright the respective owners / authors. Aletho News makes no claim of copyright on such material.
“…and I saw newspapers in London retailing these lies and eager intellectuals building emotional superstructures over events that never happened.” –George Orwell, in his memoir, Looking Back on the Spanish Civil War.
Scientists, after years of attempts, still have never come close to proving that diseases which they attribute to viruses are due to infections. After such repeated failures it’s safe to say that these sorts of infections never happen, yet this article retails the lie as a fact.
Should I believe that even though the first clause of the following sentence is a lie, the second clause, talking about the effect of the vaccines, is true?
“In contrast to disrupted germinal centres in lymph nodes during infection, mRNA vaccination stimulates robust germinal centres containing vaccine mRNA and spike antigen up to eight weeks postvaccination in some cases…”
In this world, with the way things are, I’m reduced to almost constantly asking, “what part, of what the liar said, is true?”
LikeLike
Comment by Matt | March 19, 2022 |
Is it safe to say that if a mRNA vaccinated individual has not shown signs of clotting within 6 months that they will not encounter this type of issue?
LikeLike
Comment by Jim McLaughlin | October 8, 2022 |