Vitamin D Cuts COVID-19 Risk of Death in Half, New Study Finds. So Why Isn’t it Recommended?
BY WILL JONES | THE DAILY SCEPTIC | FEBRUARY 3, 2023
Vitamin D cuts the risk of death from COVID-19 by 51% and the risk of ICU admission by 72%, a meta-analysis of randomised controlled trials has found. The new study, published in Pharmaceuticals, is titled “Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalisation and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis”. Here’s the abstract, summarising the study’s method and results.
Background: The COVID-19 pandemic represents one of the world’s most important challenges for global public healthcare. Various studies have found an association between severe vitamin D deficiency and COVID-19-related outcomes. Vitamin D plays a crucial role in immune function and inflammation. Recent data have suggested a protective role of vitamin D in COVID-19-related health outcomes. The purpose of this meta-analysis and trial sequential analysis (TSA) was to better explain the strength of the association between the protective role of vitamin D supplementation and the risk of mortality and admission to intensive care units (ICUs) in patients with COVID-19.
Methods: We searched four databases on September 20th 2022. Two reviewers screened the randomised clinical trials (RCTs) and assessed the risk of bias, independently and in duplicate. The pre-specified outcomes of interest were mortality and ICU admission.
Results: We identified 78 bibliographic citations. After the reviewers’ screening, only five RCTs were found to be suitable for our analysis. We performed meta-analyses and then TSAs. Vitamin D administration results in a decreased risk of death and ICU admission (standardised mean difference (95% CI): 0.49 (0.34–0.72) and 0.28 (0.20–0.39), respectively). The TSA of the protective role of vitamin D and ICU admission showed that, since the pooling of the studies reached a definite sample size, the positive association is conclusive. The TSA of the protective role of vitamin D in mortality risk showed that the z-curve was inside the alpha boundaries, indicating that the positive results need further studies.
Discussion: The results of the meta-analyses and respective TSAs suggest a definitive association between the protective role of vitamin D and ICU hospitalisation.
Despite these highly positive results, the latest official guidelines from NICE still state that vitamin D is not recommended for the prevention of COVID-19. (NICE also doesn’t recommend the use of ivermectin or budesonide.) Yet remdesivir is recommended despite the WHO finding little or no effect. Will NICE now update its guidelines? I wouldn’t count on it.
Dr. John Campbell discusses the new study in a recent video, arguing the evidence on vitamin D is now conclusive and wondering why adequate vitamin D supplementation is not being officially promoted in the U.K. The fact that the MHRA is 86% industry-funded may have something to do with it, he suggests.
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Book Excerpt
Begging for the Wonder Drug
By John Leake | Courageous Discourse | December 13, 2024
As I was researching our book, The Courage to Face COVID-19: Preventing Hospitalization and Death While Battling the Bio-Pharmaceutical Complex, I was especially disturbed by countless stories of hospitals in various states who steadfastly refused to treat critically ill COVID-19 patients with ivermectin and other drugs (commonly used for other illnesses) that could have saved their lives.
I believe this episode constitutes the darkest chapter in the history of the U.S. hospital system. Strangely enough, the only serious legacy newspaper journalist in the entire country who covered it was Michael Capuzzo—formerly a reporter with the Miami Herald and the Philadelphia Inquirer, where he received four Pulitzer Prize nominations. Apart from Michael’s reporting . . . crickets.
Out of my conviction that we should never forget what U.S. hospitals did to patients who were consigned to die on ventilators instead of receiving FDA-approved, off-label drugs such as ivermectin, methylprednisolone, and even high dose aspirin, I am publishing our chapter on the extraordinary villains who committed this atrocity, and the good guys—including two great attorneys and humanitarians named Ralph Lorigo and Beth Parlato—who fought back. Please share this story with your friends and family and exhort them never to forget. … continue
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