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Varicella-Zoster Reactivation after COVID-19 Illness versus SARS-CoV-2 Vaccination

Larger Ongoing Threat is COVID-19 Vaccination

By Peter A. McCullough, MD, MPH | Courageous Discourse | February 6, 2023

Many papers in the medical literature seem to pit a consequence such as myocarditis or stroke as either occurring as a consequence of COVID-19 illness compared with COVID-19 vaccination. Because the denominator is so large for acutely ill hospitalized patients with COVID-19 especially during the first two years of the pandemic allowing ICD code capture of comorbidities, authors erroneously conclude the illness is “more dangerous” or a “bigger risk factor.” These arguments are daft in my opinion since COVID-19 respiratory illness is treatable and a recent paper from Klaassen et al has estimated 94% are already recovered from COVID-19—so it is water under the bridge. Not true for COVID-19 vaccines which are still mandated by some ill-advised schools, employers, and agencies. One way of looking for what is a more pressing and continued problem is to survey the medical literature.

Martinez-Reviejo et al completed a literature review of varicella-zoster reactivation (shingles) and compared cases arising after vaccination and those with the respiratory infection. There were more manuscripts and cases after vaccination. However, the manifestations of varicella-zoster were more severe in those with acute COVID-19 illness which was also high in disease severity.

Martinez-Reviejo R, Tejada S, Adebanjo GAR, Chello C, Machado MC, Parisella FR, Campins M, Tammaro A, Rello J. Varicella-Zoster virus reactivation following severe acute respiratory syndrome coronavirus 2 vaccination or infection: New insights. Eur J Intern Med. 2022 Oct;104:73-79. doi: 10.1016/j.ejim.2022.07.022. Epub 2022 Aug 1. PMID: 35931613; PMCID: PMC9340059.

I found it curious the authors did not disclose the shingles vaccine status in the tables. The bottom line is that shingles can occur with severe COVID-19 and it is treatable. Acute COVID-19, however is amenable to early therapeutics so severe cases can be avoided and most of us have recovered SARS-CoV-2 infection. COVID-19 vaccination continues to be an ongoing threat for varicella-zoster reactivation syndromes, some of which are very serious including ocular damage and long-lasting painful cutaneous syndromes.

Klaassen F, Chitwood MH, Cohen T, Pitzer VE, Russi M, Swartwood NA, Salomon JA, Menzies NA. Changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States between December 2021 and November 2022. medRxiv [Preprint]. 2022 Nov 23:2022.11.19.22282525. doi: 10.1101/2022.11.19.22282525. PMID: 36451882; PMCID: PMC9709792.

Martinez-Reviejo R, Tejada S, Adebanjo GAR, Chello C, Machado MC, Parisella FR, Campins M, Tammaro A, Rello J. Varicella-Zoster virus reactivation following severe acute respiratory syndrome coronavirus 2 vaccination or infection: New insights. Eur J Intern Med. 2022 Oct;104:73-79. doi: 10.1016/j.ejim.2022.07.022. Epub 2022 Aug 1. PMID: 35931613; PMCID: PMC9340059.

February 8, 2023 - Posted by | Science and Pseudo-Science | ,

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