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Spain, convincing therapeutic evidence

Dr. John Campbell | February 13, 2021

Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study (October 2020)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456194/

n = 76, Calcifediol treatment

50 patients treated with calcifediol

One required admission to ICU (2%)

No deaths

26 untreated patients

13 required admission to ICU (50 %)

2 deaths

Calcifediol treatment and COVID-19-related outcomes

(22nd January)

Barna-COVIDIOL

Barcelona

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318

Effect of calcifediol treatment

In admitted patients

On ICU admission

and mortality

N = 930

Randomly assigned

Calcifediol treatment group n = 551

Day one, 532 ug (21,000 iu)

Days, 3, 7, 15, 30, 266 ug (10,640 iu)

No adverse effects reported

Required ICU, 30 (5.4%)

Deaths, 36 (6.5%)

Death RR = 0.36

64% reduced chance of death

Control group n = 379

Required ICU, 80 (21.1%), p less than 0.0001

Deaths, 57 (15%), p = 0.001

Adjusted for

Age

Sex

Comorbidities

Linearized 25(OH)D levels at baseline

Treated patients

Reduced risk to require ICU

RR 0.18

Baseline 25(OH)D levels

Inversely correlated with the risk of ICU

Predictors of reduced mortality

Higher baseline 25(OH)D levels

Predictors on increased mortality

Age

Obesity

Interpretation

In patients hospitalized with COVID-19, calcifediol treatment at the time of hospitalization significantly reduced ICU admission and mortality.

Early calcifediol after admission

Prior to ARDS development, is critical for mortality reduction

Initiation of calcifediol during ICU admission did not modify patient survival

February 21, 2021 - Posted by | Science and Pseudo-Science, Timeless or most popular, Video |

4 Comments »

  1. This may be of interest/convincing to a medical scientist; not to layman me. I did do a quick search of the never-prior-encountered word ‘calcifediol’ and found reference to a word(s) that began with ‘hydroxy….’ Is this vertically disjointed “report” some sort of endorsement by Campbell of hydroxychloroquine?

    Like

    Comment by roberthstiver | February 22, 2021 | Reply

    • Hi Robert.

      No, is the short answer but it is trying to attain the same objective – reduce inflammation in the lungs.
      The idea is to treat people before their lungs get damaged because it is then you have to do all the dangerous reanimation stuff.
      If you did not watch the video and just read I’d advise that because he explains it very well.
      This confirms that the therapeutic approaches appear to be much more effective than vaccination.
      Reported by CDC in the US via Vaccination Adverse Event Reporting (VAER) there are now more than 15000 reports for Pfizer and nearly 1000 people dead.(An adverse event means you need medical treatment)
      The other important point is that whereas hydroxychloroquine has potential (but well known and understood) side effects the introduction of large doses of Calcifediol appears to have zero side effects. So risk benefit is enormous.

      Hope this helps – video is very good as I said.

      Liked by 1 person

      Comment by redracam | February 23, 2021 | Reply

      • Thank you! I did watch the video this morning…hard for me at 77 yo to hear rapid-fire Brit English, but the good doc is obviously smart and committed to his cause. Question(s): where the hell have he and his supporters been?–can’t they break through the “wall” to WHO, UK, Spain, Fauci/CDC…? Why just throw out videos on the Internet? Don’t he and his supporters, at this juncture, merely become “hair shirts,” Monday-morning quarterbacks, conspiracy theorists…? There was a lot of political and professional/medical turmoil in the early days of the pandemic…what good does it do now to recriminate?

        I do comport (while noting youre\ “appear”…) with “…therapeutic approaches appear to be much more effective than vaccination….” Well, then, why isn’t everybody, for the “pennies per pill” indicated, using Calcifediol as a PREVENTIVE measure? I’d take it now and every day, rather than vaccination, if it were advocated and proven (as this case seems to do, persuasively). I.e. why the hell wait until a patient is already admitted to hospital/ICU…?

        These are off-the-cuff random thoughts and not well-considered (maybe I need a “peer review”?). I do sincerely appreciate your reach-out…!

        Like

        Comment by roberthstiver | February 23, 2021 | Reply

        • Hi Robert,

          I agree with you in normal circumstances where people are in good faith I would say “no finger-pointing” and let’s get on to work to a positive outcome.

          Unfortunately, there are interests at work that have profit and power as their motive and care little or nothing for real medical care for ordinary people.

          You definitely do not need a peer review. We are all the same, as usual, stumbling around in the dark trying to make sense of things. Like Israel, )/11, JFK Assassination, the Federal reserve; because of a big layer of hog-wash it takes time to understand what is going on. The Covid19 scamdemic is no different as far as I can see.

          Liked by 1 person

          Comment by redracam | February 26, 2021 | Reply


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