Antidepressants can cause ‘chemical castration’
Patients are not being warned of persistent, irreversible sexual dysfunction caused by SSRIs
BY MARYANNE DEMASI, PHD | JUNE 12, 2023
Antidepressants can cause severe, sometimes irreversible, sexual dysfunction that persists even after discontinuing the medication.
Sufferers have described it as ‘chemical castration’ – a type of genital mutilation caused by antidepressants, mainly selective serotonin reuptake inhibitors (SSRIs).
The condition is known as post-SSRI sexual dysfunction (PSSD), a condition largely unrecognised, and the true incidence of which is unknown.
David Healy, psychiatrist and founder of RxISK.org said, “I saw my first patient with PSSD in 2000, a 35-year-old lady who told me that three months after stopping treatment, she could rub a hard-bristled brush across her genitals and feel nothing.”
Josef Witt-Doerring, psychiatrist and former FDA medical officer said, “This condition is so devastating that it will cause serious changes to your life and to those around you.”
It happened to Rosie
In 2020, during protracted covid lockdowns in Melbourne, 23-year-old Rosie Tilli felt an increasing sense of anxiety and depression.
Her psychiatrist prescribed a low dose of Lexapro (escitalopram), an SSRI to help Rosie calm down, assuring her that if she experienced side effects, they’d go away once she stopped the medication.
Rosie Tilli
Soon after taking the medication Rosie felt emotionally blunted, but took it as a positive sign.
“At first, I thought it was great because it felt like the medication was working. But then I couldn’t feel my emotions, I couldn’t cry, I had no sexual desire, and my genitals went numb.”
After four months, Rosie decided to slowly wean herself off the medication. Some of her symptoms improved and the fog lifted, but over the next two years her libido faded to nothing.
“It has been two years of hell. Now, I have no sexual function. I’m numb down there. I can’t have an orgasm. It feels like my soul has just been vacuumed out of my body. I feel completely asexual,” said Rosie.
She sought help from various professionals, but none believed it could be the antidepressant because the drug had already left her system. They concluded it was all in her mind.
Rosie went to a local youth centre for help, but they ended up sectioning her under the Mental Health Act with an Involuntary Treatment Order, insisting she take antipsychotic medication.
“I refused to take an antipsychotic because I knew I wasn’t psychotic. Instead, they forced me to take another antidepressant against my will in order to leave the facility,” said Rosie.
“It was the most traumatic thing I’ve ever been through in my life. I felt helpless and my parents just looked on and said, ‘trust the professionals, they know what they are doing’.”
In her clinical notes, the doctors wrote that “Rosie exhibits fixated beliefs of a delusional intensity about ongoing sexual side effects from Lexapro”.
“One psychologist actually asked me if I’d tried seeing a male sex worker to help bring back my libido. I was shocked. They said it would reduce my anxiety and help me get in touch with my body,” said Rosie.
“I’m chemically castrated, and no one believes me. In retrospect, my original anxiety was not even a problem compared to this. This has absolutely ruined my quality of life. I feel trapped inside my own body,” she added.
Doctors don’t get it
“Most doctors are not familiar with enduring side effects following antidepressants and believe side effects end after the drug is discontinued,” said Witt-Doerring.
“There’s a lot of shame wrapped up in sexual functioning, especially in young persons. Even older persons don’t want to talk about it and so they’re not reporting it, or they are minimising the sexual aspects of their symptoms to their doctors,” he added.
Healy says PSSD is often dismissed as the person’s ‘underlying depression’ and patients are gaslighted by their doctors leading to repeated trauma.
“I’ve known many patients who’ve gone on to commit suicide because of the condition. Others have asked for referrals to Dignitas, which is access to assisted dying in Switzerland,” said Healy.
PSSD has been discussed in the medical literature for about 15 years, but very few studies focus on the issue.
In a study from 2001 involving >1000 patients with no previous history of sexual problems, 59% reported sexual dysfunction after commencing an antidepressant. For the five most commonly used drugs, 46% experienced no orgasm or ejaculation.
A 19-year retrospective cohort analysis recently published in the Annals of General Psychiatry, found that 1 in 216 males taking a serotonergic antidepressant (80% took an SSRI) experienced erectile dysfunction long after discontinuing their medication.
Sufferers have gone to extreme lengths to find a treatment, or even an explanation, for their condition.
Some have had biopsies to see if the medication has damaged their sensory nerves – others have had plasmapheresis, to mop up rogue antibodies in their system.
None of it works.
“The truth is, there’s no unifying, readily agreed upon cause for why these people are experiencing these symptoms. It remains unknown,” said Witt-Doerring.
Drug regulators
In 2018, Healy led a group of physicians and researchers who petitioned the US Food and Drug Administration (FDA) “to immediately require the addition of boxed warnings and precautions on the product’s label.”
Healy said the petition sought to highlight the harms of SSRIs by adding warnings about harms such as ‘genital anaesthesia’ and requested that the FDA send ‘Dear Doctor’ letters to all medical professionals about the significant public health concern these drugs pose.
However, to date, the FDA has not responded to the petition. Nor has the agency responded to follow up enquiries. Healy says he had more success with the European regulator.
In June 2019, the European Medicines Agency updated the ‘Special Warnings and Precautions’ section on the label of SSRIs to warn that sexual dysfunction can persist even after treatment stops.
In 2021, Health Canada also did a review of the evidence and “found rare cases of long-lasting sexual symptoms persisting after stopping SSRI or SNRI treatment” and updated the product label for Canadians.
“The problem is that doctors in Europe and Canada might not be checking the drug labels now that the warnings have been updated. And there were no letters sent to medical professionals to alert them of the new warnings,” said Witt-Doerring.
In Australia, the product label of Lexapro (the drug that Rosie was prescribed) does not have any warnings about permanent or long-lasting sexual dysfunction.
A spokesperson for the TGA said that the agency was aware of the actions taken by EMA and Health Canada to update the product labels in those countries. It stated:
The TGA is actively considering appropriate regulatory actions in response to our own review of the evidence, noting that the Australian PIs of some SSRI and SNRI products have already been updated by the relevant sponsors.
Lack of informed consent
“There’s a massive epidemic of a lack of informed consent,” said Witt-Doerring.
“For most people, they would want to know about reports of persistent and enduring sexual dysfunction; it would weigh on the decision for them to take this medication,” he added.
Rosies’s doctor failed to warn her about PSSD, despite EMA’s label update in 2019.
“It has been two years since I stopped the medication, and all the symptoms are progressively getting worse. I am unable to feel myself peeing, I can’t feel a crush or romantic emotions, I can’t feel love, happiness, joy, or euphoria,” said Rosie.
“I would have been OK to have difficulty with orgasm or low libido while I was on the drug, but I never thought that I could lose all sensation in my genitals, and that it would be permanent. I would never have touched the drug if I’d known it was a possibility,” she added.
A website has been dedicated to increasing awareness of PSSD and gives people the opportunity to tell their stories.
Share this:
Related
June 14, 2023 - Posted by aletho | Deception, Timeless or most popular | Lexapro, SSRIs
2 Comments »
Leave a comment Cancel reply
This site uses Akismet to reduce spam. Learn how your comment data is processed.
Featured Video
Israeli forces killed 8-year-old Ritaj’s family
or go to
Aletho News Archives – Video-Images
Book Review
Got His Gun: Lost His Legs, Arms, and Penis
By David Swanson | War is a Crime | October 27, 2013
Ann Jones’ new book, They Were Soldiers: How the Wounded Return from America’s Wars: The Untold Story, is devastating, and almost incomprehensibly so when one considers that virtually all of the death and destruction in U.S. wars is on the other side. Statistically, what happens to U.S. troops is almost nothing. In human terms, it’s overwhelming.
Know a young person considering joining the military? Give them this book.
Know a person not working to end war? Give them this book.
Jones presents the choice before us in the clearest terms in the introduction:
Contrary to common opinion in the United States, war is not inevitable. Nor has it always been with us. War is a human invention — an organized, deliberate action of an anti-social kind — and in the long span of human life on Earth, a fairly recent one. For more than 99 percent of the time that humans have lived on this planet, most of them have never made war. Many languages don’t even have a word for it. Turn off CNN and read anthropology. You’ll see.
What’s more, war is obsolete. Most nations don’t make war anymore, except when coerced by the United States to join some spurious ‘coalition.’ The earth is so small, and our time here so short. No other nation on the planet makes war as often, as long, as forcefully, as expensively, as destructively, as wastefully, as senselessly, or as unsuccessfully as the United States. No other nation makes war its business.
Jones begins her book with that distinguishing feature of war: death. The U.S. military assigns specialists in “Mortuary Affairs” to dispose of the dead. They dispose of their own sanity in the process. … continue
Blog Roll
-
Join 2,755 other subscribers
Visits Since December 2009
- 6,735,404 hits
Looking for something?
Archives
Calendar
Categories
Aletho News Civil Liberties Corruption Deception Economics Environmentalism Ethnic Cleansing, Racism, Zionism Fake News False Flag Terrorism Full Spectrum Dominance Illegal Occupation Mainstream Media, Warmongering Malthusian Ideology, Phony Scarcity Militarism Progressive Hypocrite Russophobia Science and Pseudo-Science Solidarity and Activism Subjugation - Torture Supremacism, Social Darwinism Timeless or most popular Video War Crimes Wars for IsraelTags
9/11 Afghanistan Africa al-Qaeda Australia BBC Benjamin Netanyahu Brazil Canada CDC Central Intelligence Agency China CIA CNN Colombia Covid-19 COVID-19 Vaccine Da’esh Donald Trump Egypt European Union Facebook FBI FDA France Gaza Germany Google Hamas Hebron Hezbollah Hillary Clinton Human rights India Iran Iraq ISIS Israel Israeli settlement Japan Jerusalem Joe Biden Korea Latin America Lebanon Libya Middle East National Security Agency NATO New York Times North Korea NSA Obama Pakistan Palestine Qatar Russia Sanctions against Iran Saudi Arabia Syria The Guardian Turkey Twitter UAE UK Ukraine United Nations United States USA Venezuela Washington Post West Bank WHO Yemen ZionismRecent Comments
Aletho News
- Meta’s Oversight Board Adopts International “Norms” Instead of US Free Speech Principles
- RFK Jr. Files Lawsuit Against Meta, Alleging Censorship of Presidential Campaign Video
- Woman Injured by AstraZeneca COVID Vaccine During Clinical Trial Sues for Breach of Contract
- Strategic setbacks for US, Israel as the Resistance Axis gains ground in Syria
- Vulcan Program’s Delay Shows US Can’t Even Copy, Much Less Replace, Russia’s Rocket Engine Know-How
- The U.S. Defeat in Vietnam Changed Nothing
- Firing Blanks: The Pentagon as a Fiscal Disaster Factory
- Russia’s Belousov, Shoigu to Take Part in Informal Putin-Xi Meeting – Kremlin Aide
- Ukrainian military stole money intended for fortifications – media
- Is the U.S. blackmailing India over assassination allegations to be more hostile toward China and Russia?
If Americans Knew
- Knowledge is going up in smoke in Gaza
- Israeli settlers destroy truckloads of aid, as Israeli forces watch, Gazans starve – Day 220
- Who’s Funding AIPAC’s Political Spending Barrage?
- For Columbia and a Powerful Donor, Months of Talks and Millions at Risk
- Columbia crackdown led by university prof doubling as NYPD spook
- Disaster unfolds all over Gaza, West Bank – Day 219
- Israeli airstrikes in southern Gaza, invasion in central Gaza, carpet bombing in north – Day 218
- Strapped down, blindfolded, held in diapers: Israeli whistleblowers detail abuse of Palestinians in shadowy detention center
- Fighter jets, attack drones hammer Rafah; catastrophe looms – Day 217
- What it’s like to be used as a human shield by the Israeli army
Richie Allen
- The Richie Allen Show Returns Tomorrow Wednesday April 24th
- Call Richie Today Monday March 11th From 4.30pm
- Connect To The Richie Allen Show WhatsApp Today
- NHS Asks Patients To Choose From 12 Genders, 10 sexual Preferences & 159 Religions
- The Richie Allen Show Moves To A New Time Slot From Monday Nov 20th
- Starmer Will Sack Shadow Ministers Who Vote For Gaza Ceasefire
- AI Tool Can Predict Heart Attacks Years In Advance
- Nepal Bans TikTok To Preserve Social Harmony
- Bloke Appointed Boss Of Womb Health Charity
- WHO – “Gaza’s Biggest Hospital Becoming A Cemetery”
No Tricks Zone
- Using Nets On The Seafloor To Retrieve Seafood ‘Roughly The Same As Running 100 Coal-Fired Plants’
- New Paper: Global Warming Leading To HIMALAYAN COOLING, Preventing Glacial Melt!
- DNA Evidence Reveals Domestic Cats, Dogs, African Wildcats, Frogs Lived In The Arctic 9000 Years Ago
- -80°C: Antarctic Vostok Station Records “Extreme Winter Cold”…Not Even Winter Yet!
- The German E-Vehicle Nightmare, 2024 Q1 Sales Plummet 14%… “Graveyard” For Unsold Cars
- Newly Discovered 90,000-Year-Old Human Footprints Reveal How Much Higher Sea Levels Used To Be
- Germany’s Economic Bloodbath Worsens As Green Revolution Causes Economy To Bleed To Death
- Water Vapor Absorbs 84 Times More Radiation Than CO2 … Clouds Drove 89% Of 1982-2018 Warming
- The 97% Consensus Claim Is In Fact 97% Bogus
- Post-1980s Increases In Shortwave Radiation Explains Europe’s Warming Trends Far Better Than CO2
More Links
Contact:
atheonews (at) gmail.com
Disclaimer
This site is provided as a research and reference tool. Although we make every reasonable effort to ensure that the information and data provided at this site are useful, accurate, and current, we cannot guarantee that the information and data provided here will be error-free. By using this site, you assume all responsibility for and risk arising from your use of and reliance upon the contents of this site.
This site and the information available through it do not, and are not intended to constitute legal advice. Should you require legal advice, you should consult your own attorney.
Nothing within this site or linked to by this site constitutes investment advice or medical advice.
Materials accessible from or added to this site by third parties, such as comments posted, are strictly the responsibility of the third party who added such materials or made them accessible and we neither endorse nor undertake to control, monitor, edit or assume responsibility for any such third-party material.
The posting of stories, commentaries, reports, documents and links (embedded or otherwise) on this site does not in any way, shape or form, implied or otherwise, necessarily express or suggest endorsement or support of any of such posted material or parts therein.
The word “alleged” is deemed to occur before the word “fraud.” Since the rule of law still applies. To peasants, at least.
Fair Use
This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a ‘fair use’ of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more info go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond ‘fair use’, you must obtain permission from the copyright owner.
DMCA Contact
This is information for anyone that wishes to challenge our “fair use” of copyrighted material.
If you are a legal copyright holder or a designated agent for such and you believe that content residing on or accessible through our website infringes a copyright and falls outside the boundaries of “Fair Use”, please send a notice of infringement by contacting atheonews@gmail.com.
We will respond and take necessary action immediately.
If notice is given of an alleged copyright violation we will act expeditiously to remove or disable access to the material(s) in question.
All 3rd party material posted on this website is copyright the respective owners / authors. Aletho News makes no claim of copyright on such material.
How do you personally treat MDD, Dr. Demasi? You could have mentioned alternatives to SSRIs.
LikeLike
Comment by Victor G. | June 15, 2023 |
I commiserate totally with your predicament. Currently am undergoing treatment for Prostate Cancer. I have been told I cannot be operated on because I have an anurysum close to my lymph nodes which could be punctured during any removal operation. So they opted for chemical and radiation treatment. The chemical consists of FEMALE HORMONS called EPIGARD. This is injected into my stomach muscles every three months and is allegedly preventing the manufacture of Testosteron, which I am told is the food the cancer cells thrive upon. Unfortunately, this female hormoun has serious side effects, one of which is sexual disfunction as without testosteron the male part cannot function. I’m comfortable with that, provided I see some positive results in the cancer treatment.
However, given the above information, I’d suggest exploring the uptake of this female hormoun yourself, maybe it could kick start your sexual function once again.
LikeLike
Comment by itchyvet | June 15, 2023 |