Pharmageddon: America’s bitter pill
RT | December 27, 2011
The United States has a passion for pills, being the world’s biggest users of psychotropic drugs, consuming 60 per cent of them. And pharmaceutical firms are keen to keep cashing in on the multibillion-dollar market, even if it costs people’s health.
America is regarded as a country with a prodigious appetite for consumption. Today, a widespread fondness for pharmaceuticals has turned the US into a nation of pill-poppers.
With over $14 billion in annual sales, antipsychotics remain the top-selling therapeutic class of prescription drugs in the US.
Dr. Harriet Fraad believes Big Pharma has manufactured a climate of insanity by manipulating and even creating illness for capital gain.
“One of the things that drives Big Pharma is to find a diagnosis that is very vague, so that everybody can fall into that,” she told RT. “Everybody is sad sometimes. There are good reasons. The point is to market pharmaceuticals. And the advertising strategy is to have vague diagnosis and then find wiggle room so that they apply to everyone.”
The US is the only Western country that allows direct-to-consumer advertising of prescription drugs. For example, an ad for Attention Deficit Hyperactivity Disorder warns that untreated patients will likely end up divorced. Another commercial promises to make you happier, but side-effects may include dry mouth, insomnia, sexual dysfunction, diarrhea, nausea and sleepiness.”
Critics also say Big Pharma uses its financial muscle to ply doctors with gifts, cash kick-backs and research funding in exchange for endorsing or prescribing the latest and most lucrative drugs.
Harriet Fraad says there is a whole network of doctors hustling these drugs.
“If a patient comes in with a knee injury and says, ‘I’m so sad.’ Oh, are you depressed? Hey write a prescription! They’re given out like M&Ms.”
Last year, prescription drug abuse became the number one cause of accidental death, with more than 30,000 Americans overdosing.
For instance, Seroquel, medication for bi-polar disorder, generated $4.4 billion in sales last year.Listing all its side-effects requires 49 seconds of air-time.
The number of children consuming antipsychotic medication has doubled in the past decade. Millions of American adolescents are taking drugs like Adderall, doled out by doctors to treat hyperactivity.
Author of Surviving America’s Depression Epidemic, psychologist Bruce Levine, told RT that, “All these drugs are very similar to illicit or illegal drugs, except they’re more dangerous. Marijuana is a little safer. But kids have no choice.”
Pfizer, America’s most profitable multinational pharmaceutical company makes anti-depressants not only for people, but also for animals. In 2009, the pharmaceutical giant paid $2.3 billion to settle civil and criminal allegations over illegally marketing one of its drugs. It was the largest healthcare fraud settlement and criminal fine in US history.That being said, the fine amounted to less than three weeks of Pfizer’s drug sales.
“The money is so huge that the fines are immaterial. They’re not thinking about the social effects of what they’re doing. They’re thinking about the profits they accrue,” says psychotherapist Harriet Fraad.
The pharmaceutical industry remains the most profitable business in the US. More success and financial gain for the companies will always remain possible as long as more Americans are encouraged to take drugs.
Conflicts of interest in climate science
By Judith Curry | Climate Etc. | February 25, 2015
Once you tug on the thread of undisclosed financial interests in climate science, you’ll find it more a norm than exception. – Roger Pielke Jr (tweet)
Context
I started working on this post last week, in response to the Willie Soon imbroglio. This whole issue has now become personal.
In case you haven’t been following this, Justin Gillis broke the story on Willie Soon with this article Deeper Ties to Corporate Cash for Doubtful Climate Researcher. The Smithsonian issued the following statement on the issue of Soon’s funding and apparent failure to disclose this funding in journal publications. Science Magazine has a summary [here] and Nature has a summary [here].
The ‘plot’ thickened yesterday, as Arizona Congressman Raul Grijalva (Democrat) Asks for Conflict-of-Interest Disclosures from GOP’s Go-To Climate Witnesses [link]. Excerpts:
The conflict-of-interest scandal involving a climate denier secretly funded by the fossil-fuel industry is spreading to other academics who oppose regulation of climate pollution. A top House Democrat has issued letters asking several researchers who have appeared as Republican witnesses before Congress questioning climate science to disclose their funding sources.
“I am hopeful that disclosure of a few key pieces of information will establish the impartiality of climate research and policy recommendations published in your institution’s name and assist me and my colleagues in making better law,” Grijalva wrote. “Companies with a direct financial interest in climate and air quality standards are funding environmental research that influences state and federal regulations and shapes public understanding of climate science. These conflicts should be clear to stakeholders, including policymakers who use scientific information to make decisions. My colleagues and I cannot perform our duties if research or testimony provided to us is influenced by undisclosed financial relationships.”
The letters request the institutions’ disclosure policies, drafts and communications relating to Congressional testimony, and sources of external funding for the academics in question.
The disclosure requests are needed because Congressional “truth in testimony” rules require witnesses to disclose government funding sources, but not private or corporate funding. Under Republican control, the rules are unevenly implemented, with not-for-profit witnesses required to submit pages of additional disclosures, while corporate-sector witnesses are not.
The seven academics who dispute the scientific consensus on anthropogenic global warming who have been asked to disclose their funding are:
David Legates, John Christy, Judith Curry, Richard Lindzen, Robert Balling, Roger Pielke Jr., Steven Hayward.
A copy of the letter from Grijalva that was sent to President Peterson of Georgia Tech is [here].
An article in ClimateWire provides additional context [link].
Skip to JC reflections for my punch line.
Conflict in scientific publication
Conflict of interest related to industry funding is a very big issue in biomedical research (related to drug and food safety) and also related to environmental contaminants. It isn’t a big issue in other scientific fields. Apart from expecting scientists to describe funding sources in the Acknowledgements, many journals don’t even have any conflict of interest disclosure requirements.
For those journals that do have such requirements, the requirements for disclosure are vastly different. As examples:
Nature : In the interests of transparency and to help readers to form their own judgements of potential bias, Nature journals require authors to declare to the editors any competing financial interests in relation to the work described. The corresponding author is responsible for submitting a competing financial interests statement on behalf of all authors of the paper. Authors submitting their manuscripts using the journal’s online manuscript tracking system are required to make their declaration as part of this process and to specify the competing interests in cases where they exist. The definition of conflict of interest relates to funding sources, employment, and personal financial interests.
Science : Science goes further with this statement: Management/Advisory affiliations: Within the last 3 years, status as an officer, a member of the Board, or a member of an Advisory Committee of any entity engaged in activity related to the subject matter of this contribution. Please disclose the nature of these relationships and the financial arrangements. Within the last 3 years, receipt of consulting fees, honoraria, speaking fees, or expert testimony fees from entities that have a financial interest in the results and materials of this study.
Wow. I haven’t published anything in Science in recent years (and never as a first author). So, all those scientists serving on Boards of green advocacy groups [Climate Scientists Joining Green Advocacy Groups] who publish in Science on any environmental or climate change topic should be declaring a conflict of interest.
So, once an author of a climate change paper declares a conflict of interest, what is that supposed to mean? An article in Science Magazine addresses this issue:
Conflict-of-interest controversies are rare in her field, she notes, and “they can be tricky.” Conflict is often in the eye of the beholder, she says, and researchers often accept all kinds of funding that doesn’t necessarily skew their peer-reviewed publications. “I’m for full disclosure,” she says, “but I’m not sure how we’re going to address this.” The journal, published by Elsevier, asks authors to fill out a conflict-of-interest disclosure. But Strangeway admits he’s never carefully examined one—and isn’t sure what he’s supposed to do if he sees a red flag. “We wouldn’t be raising the journal issue if [Soon] had simply disclosed Southern’s support,” he says.
Scientific journals are being alerted by watchdog groups to fossil fuel funding of contrarian climate studies [link]. Are we not to be concerned by fossil fuel funding of consensus climate science (there is plenty of that, see below)? Are we not to be concerned by funding from green advocacy groups and scientists serving on the Boards of green advocacy groups?
DeSmog surprised me with this article: How often were Willie Soon’s Industry-funded Deliverables Were Referenced by the IPCC? I was surprised to find that published journal papers with ties to industry made it into the IPCC, to counter all those gray literature articles by Greenpeace et al.
So, in climate science, what is the point of conflict of interest disclosure? Bishop Hill sums it up this way:
As far as I can see, the story is that Soon and three co-authors published a paper on climate sensitivity. At the same time (or perhaps in the past – this being a smear-job it’s hard to get at the facts) he was being funded to do work on things like the solar influence on climate by people that greens feel are the baddies. They and the greens feel he should have disclosed that baddies were paying him to do stuff on a paper that was not funded by the baddies.
The issue is this. The intense politicization of climate science makes bias more likely to be coming from political and ideological perspectives than from funding sources. Unlike research related to food and drug safety and environmental contaminants, most climate science is easily replicable using publicly available data sets and models. So all this IMO is frankly a red herring in the field of climate science research.
Bottom line: Scientists, pay attention to conflict of interest guidelines for journals to which you are submitting papers. Select journals that have COI disclosure requirements that are consistent with your comfort level.
Conflict in Testimony
The HillHeat article provides links to the relevant testimony by the 7 individuals (see original article for actual links):
- David Legates, Department of Agricultural Economics & Statistics, University of Delaware climatologist (6/3/14, 7/29/03, 3/13/02)
- John Christy, University of Alabama atmospheric scientist (12/11/13, 9/20/12, 8/1/12, 3/31/11, 3/8/11, 2/25/09, 7/27/06 (video), 5/13/03, 5/2/01, 5/17/00, 7/10/97)
- Judith Curry, Georgia Institute of Technology climatologist (1/16/14, 4/25/13, 11/17/10)
- Richard Lindzen, Massachusetts Institute of Technology atmospheric physicist (11/17/10, 5/2/01, 7/10/97, 1991 (Senate), 10/8/91)
- Robert C Balling Jr, Arizona State University geographer (3/6/96; North Carolina Legislature 3/20/06)
- Roger Pielke Jr, University of Colorado political scientist (12/11/13, 7/18/13, 3/8/11, 5/16/07, 1/30/07 (video), 7/20/06, 3/13/02)
- Steven Hayward, School of Public Policy, Pepperdine University historian (5/25/11, 10/7/09, 4/22/09, 3/12/09, 3/17/99)
HOLD ON. The article ‘forgot’ to reference my earlier testimony for the Democrats in 2006, 2007:
- House Committee on Govt Reform, “Hurricanes and Global Warming,” 7/20/06 [link]
- House Select Committee on Energy Independence and Global Warming, “Dangerous Climate Change,” 4/26/07 [link]
I can see that this earlier testimony is ‘inconvenient’ to their argument.
When you testify, you are required to include a financial disclosure related to your government funding. Presumably this is relevant if you are testifying with relation to performance by a government agency. There is no disclosure requirement that is relevant to individuals from industry or advocacy groups, or for scientists receiving funding from industry or advocacy groups.
To clarify my own funding, I have included the following statement of financial interests at the end of my testimony:
Funding sources for Curry’s research have included NSF, NASA, NOAA, DOD and DOE. Recent contracts for CFAN include a DOE contract to develop extended range regional wind power forecasts and a DOD contract to predict extreme events associated with climate variability/change having implications for regional stability. CFAN contracts with private sector and other non-governmental organizations include energy and power companies, reinsurance companies, other weather service providers, NGOs and development banks. Specifically with regards to the energy and power companies, these contracts are for medium-range (days to weeks) forecasts of hurricane activity and landfall impacts. CFAN has one contract with an energy company that also includes medium-range forecasts of energy demand (temperature), hydropower generation, and wind power generation. CFAN has not received any funds from energy companies related to climate change or any topic related to this testimony.
I note that during congressional questioning, I was never asked anything about my funding sources.
Again, I think that biases in testimony related to climate change are more likely to be ideological and political than related to funding.
So what is the point of asking for detailed financial information (including travel) from these academic researchers?
Intimidation and harassment is certainly one reason that comes to mind. Roger Pielke Jr seems to think this is the case, as described in his blog post I am Under Investigation:
I have no funding, declared or undeclared, with any fossil fuel company or interest. I never have. Representative Grijalva knows this too, because when I have testified before the US Congress, I have disclosed my funding and possible conflicts of interest. So I know with complete certainty that this investigation is a politically-motivated “witch hunt” designed to intimidate me (and others) and to smear my name.
The relevant issue to my mind is to expect non-normative testimony from academic researchers. I discussed this issue on a previous blog post Congressional testimony and normative science. Consensus climate scientists routinely present normative testimony, along the lines of ‘urgent mitigation action needed’. On the other hand, I personally work to make my testimony non-normative, and I would judge Christy’s and Pielke Jr’s testimony to be generally non-normative also (note Christy and Pielke Jr are the two on the list of 7 that I know best).
‘Dirty’ money?
The issue of concern of Congressman Grijalva is funding from the Koch brothers and fossil fuel companies somehow contaminating Congressional testimony from scientists invited by Republicans to testify.
The reality is that fossil fuel money is all over climate research, whether pro or con AGW. Gifts of $100M+ have been made by oil companies to Stanford and Princeton. Anthony Watts notes the prominence of oil companies in funding the American Geophysical Union [link]. The Sierra Club and the Nature Conservancy take fossil fuel money [link]. The UKMetOffice has stated that energy companies are major customers.
NRO has an article Follow the Money, excerpt:
In truth, the overwhelming majority of climate-research funding comes from the federal government and left-wing foundations. And while the energy industry funds both sides of the climate debate, the government/foundation monies go only toward research that advances the warming regulatory agenda. With a clear public-policy outcome in mind, the government/foundation gravy train is a much greater threat to scientific integrity.
With federal research funding declining in many areas, academics at universities are being encouraged to obtain funding from industry.
I have to say I was pretty intrigued by Soon’s funding from the Southern Company. Southern Company (SoCo) provides power to Georgia. Georgia Power (a SoCo subsidiary) has provided considerable funding to Georgia Tech (although I have never received any). For most of the time that I was Chair, the School of Earth and Atmospheric Sciences had an endowed Chair from Georgia Power. When the faculty member left Georgia Tech, I chose not to hire a replacement, since I felt that my faculty hiring funds would be more productively used on younger faculty members in different research areas. I also note that one of my faculty members received funds from Georgia Power that was a ‘charitable donation’, without overhead and without deliverables. I also ‘heard’ that Southern Company/Georgia was very unhappy with the Webster et al. 2005 paper on hurricanes [link]. Note, I have received no funding from SoCo/GaPower.
JC reflections
My first reaction to this was to tweet: Looks like I am next up in this ‘witch hunt’. My subsequent reactions have been slowed by a massive headache (literally; cause and effect?)
It looks like it is ‘open season’ on anyone who deviates even slightly from the consensus. The political motivations of all this are apparent from barackobama.com: Call Out The Climate Deniers.
It is much easier for a scientist just to ‘go along’ with the consensus. In a recent interview, as yet unpublished, I was asked: I’ve seen some instances where you have been called a “denier” when it comes to climate change, I am just curious as to your opinion on that? My reply:
As a scientist, I am an independent thinker, and I draw my own conclusions about the evidence regarding climate change. My conclusions, particularly my assessments of high levels of uncertainty, differ from the ‘consensus’ of the Intergovernmental Panel on Climate Change (IPCC). Why does this difference in my own assessment relative to the IPCC result in my being labeled a ‘denier’? Well, the political approach to motivate action on climate change has been to ‘speak consensus to power’, which seems to require marginalizing and denigrating anyone who disagrees. The collapse of the consensus regarding cholesterol and heart disease reminds us that for scientific progress to occur, scientists need to continually challenge and reassess the evidence and the conclusions drawn from the evidence.
Well, the burden is on Georgia Tech to come up with all of the requested info. Georgia Tech has a very stringent conflict of interest policy, and I have worked closely in the past with the COI office to manage any conflicts related to my company. Apart from using up valuable resources at Georgia Tech to respond to this, there is no burden on me.
Other than an emotional burden. This is the first time I have been ‘attacked’ in a substantive way for doing my science honestly and speaking up about it. Sure, anonymous bloggers go after me, but I have received no death threats via email, no dead rats delivered to my door step, etc.
I think Grijalva has made a really big mistake in doing this. I am wondering on what authority Grijalva is demanding this information? He is ranking minority member of a committee before which I have never testified. Do his colleagues in the Democratic Party support his actions? Are they worried about backlash from the Republicans, in going after Democrat witnesses?
I don’t think anything good will come of this. I anticipate that Grijalva will not find any kind of an undisclosed fossil fuel smoking gun from any of the 7 individuals under investigation. There is already one really bad thing that has come of this – Roger Pielke Jr has stated:
The incessant attacks and smears are effective, no doubt, I have already shifted all of my academic work away from climate issues. I am simply not initiating any new research or papers on the topic and I have ring-fenced my slowly diminishing blogging on the subject. I am a full professor with tenure, so no one need worry about me — I’ll be just fine as there are plenty of interesting, research-able policy issues to occupy my time. But I can’t imagine the message being sent to younger scientists. Actually, I can: “when people are producing work in line with the scientific consensus there’s no reason to go on a witch hunt.”
Drug-Induced Dementia isn’t Alzheimer’s
By Dr. Gary G. Kohls | Global Research | February 26, 2015
“More than 50 conditions can cause or mimic the symptoms of dementia.” and “Alzheimer’s (can only be) distinguished from other dementias at autopsy.” – from a Harvard University Health Publication entitled What’s Causing Your Memory Loss? It Isn’t Necessarily Alzheimer’s
“Medications have now emerged as a major cause of mitochondrial damage, which may explain many adverse effects. All classes of psychotropic drugs have been documented to damage mitochondria, as have statin medications, analgesics such as acetaminophen, and many others.” – Neustadt and Pieczenik, authors of Medication-induced Mitochondrial Damage and Disease
“Establishing mitochondrial toxicity is not an FDA requirement for drug approval, so there is no real way of knowing which agents are truly toxic.” – Dr. Katherine Sims, Mass General Hospital –http://www.mitoaction.org
“It is difficult to get a man to understand something, when his salary depends upon his not understanding it!” – Upton Sinclair, anti-fascist, anti-imperialist American author who wrote in the early 20thcentury
“No vaccine manufacturer shall be liable… for damages arising from a vaccine-related injury or death.” – President Ronald Reagan, as he signed The National Childhood Vaccine Injury Act (NCVIA) of 1986, absolving drug companies from all medico-legal liability when children die or are disabled from vaccine injuries.
Over the past several decades there have been a number of well-financed campaigns, promoted by well-meaning laypersons, to raise public awareness to the plight of patients with dementia. Suspiciously, most of these campaigns that come from “patient support” groups lead the public to believe that every dementia patient has Alzheimer’s dementia (AD).
Not so curiously, it turns out that many – perhaps all – of these campaigns have been funded – usually secretly – by the very pharmaceutical companies that benefit economically by indirectly promoting the sale of so-called Alzheimer’s drugs. Such corporate-generated public relations “campaigns” are standard operating procedure for all of BigPharma drugs, especially its psychopharmaceutical drugs. BigPharma has found that the promotion and de-stigmatization of so-called “mental illnesses” (for which there are FDA-approved drugs) is a great tool for marketing their drugs.
Recently Alzheimer’s support groups all around the nation have been sponsoring the documentary about country singer Glen Campbell who has recently been diagnosed by his physicians with Alzheimer’s disease (of unknown etiology) despite the obvious fact that Campbell was infamous for his chronic heavy use of brain-damaging, dementia-inducing, addicting, and very neurotoxic drugs like cocaine and alcohol. And, just like so many other hard-living celebrities like the recently suicidal Robin Williams, Campbell was known to have received prescriptions of legal drugs from their prescribing boutique psychiatrists and physicians, just adding to the burden that their failing livers, brains and psyches had to endure.
Since it is known that Alzheimer’s disease can only be truly diagnosed by a microscopic examination of the cerebral cortex (at autopsy), we have to question the very alive Glen Campbell’s diagnosis. And we also have to question the veracity and motivations of the sponsoring patient support groups and their BigPharma sponsors.
Is the Alzheimer’s Epidemic Actually a Drug-Induced Dementia Epidemic?
Synchronous with the huge increases (over the past generation or so) in
1) the incidence of childhood and adult vaccinations,
2) the widespread use of psychotropic and statin (cholesterol-lowering) drug use, and
3) the increased ingestion of a variety of neurotoxic substances – including food additives, there has been a large parallel increase in the incidence of
a) chronic illnesses of childhood, including autistic spectrum disorders,
b) “mental illnesses of unknown origin”, and also
c) dementia, a multifactorial reality which, via clever marketing and the studied ignorance of what is scientifically known about the actual causes – and diagnosis – of dementia, which has been primarily – and mistakenly – referred to as Alzheimer’s disease (of unknown etiology).
It is important to ask and then demand an honest answer to the question “could there be a connection between America’s increasingly common over-prescribing of immunotoxic, neurotoxic, synthetic prescription drugs and vaccines and some of the neurodegenerative disorders that supposedly “have no known cause”?
Could the economically disabling American epidemic of autoimmune disorders, psychiatric disorders, autism spectrum disorders, etc (all supposedly of unknown origin) that have erupted over the past several decades be found to have recognizable root causes and therefore be treatable and, most importantly, preventable?
These are extremely important questions, especially in the case of the current dementia epidemic, because the so-called Alzheimer’s patient support groups seem to be totally unaware of the powerful evidence that prescription drugs known to damage brain cells (especially by poisoning their mitochondria) would be expected to cause a variety of neurological and psychological disorders because of the brain cell death that eventually happens when enough of the mitochondria (the microscopic hearts and lungs of every cell) have been wounded irretrievably or killed off. (See more info on drugs and mitochondria below.)
One of the big problems in America’s corporate-controlled culture, corporate-controlled media and corporate-controlled medical industries is that the giant pharmaceutical corporations, who are in the business of developing, marketing and selling known mitochondrial toxins (in the form of their drugs and vaccine ingredients) have a special interest in pretending that there is no known cause for the disorders that their synthetic chemicals are causing (or they use the unprovable “it’s probably genetic” subterfuge).
It should be a concern of everybody who knows a demented patient, that some AD patient support groups are known to be front groups for the pharmaceutical companies that profit from the marketing to patients and their doctors the disappointingly ineffective drugs for Alzheimer’s like Aricept, Exelon, Namenda, Hexalon, and Razadyne.
Prescription Drug-Induced – and Vaccine-Induced – Mitochondrial Disorders
Acquired mitochondrial disorders (as opposed to the relatively rare primary mitochondrial disorders like muscular dystrophy) that can be caused by commonly prescribed drugs are difficult to diagnose and are generally poorly understood by most practitioners. When I went to med school, nobody knew anything about what synthetic drugs or vaccines did to the mitochondria.
A lot of mitochondrial research, especially since the 1990s, has proven the connections between a variety of commonly prescribed medications and mitochondrial disorders. That evidence seems to have been cunningly covered-up by the for-profit pharma groups (who control medical education and much of the media) and various other powers-that-be because of the serious economic consequences if the information was allowed in the popular press. The stake-holders in the pharmaceutical and medical industries, most of whom profit mightily from the routine and increasing usage of neurotoxic drugs and vaccines, supposedly operating in the name of Hippocrates, would be very displeased if this information got out. I submit that BigPharma’s cover-up of the connections is totally unethical and, in the opinion of many other whistleblowers, criminal.
An Honest Patient Guide for Dementia Patients from Harvard!
So I was pleasantly surprised to find a reasonably honest guide for dementia patients on a Harvard University website.
(The entire guide can be accessed at http://www.helpguide.org/harvard/whats-causing-your-memory-loss.htm#top.)
The information at that website stated that there were over 50 conditions that could cause or mimic early dementia symptoms. I hadn’t been taught anything about that reality when I went to med school, and I doubt that many of my physician colleagues were either. And besides, what medical practitioner in our double-booked clinic environment, even if he or she was aware, has the time to thoroughly rule out the 50 conditions when confronted with a patient with memory loss?
I have often said to my patients and my seminar participants: “it takes only 2 minutes to write a prescription, but it takes 20 minutes to not write a prescription”. And in the current for-profit clinic culture, time is money and few physicians are given the “luxury” of spending adequate time with their patients. (In defense of the physicians that I know, they are not happy about that reality but don’t know what to do about it.)
It is so tempting to use the popularized, but rather squishy label of AD (of unknown etiology) rather than to educate ourselves about the possibility of drug- or vaccine-induced dementia. But what is so important is that many of the 50+ conditions are preventable or reversible, which will be therapeutic only if the conditions are identified before permanent brain damage occurs.
The Harvard guide actually said that “medications are common culprits in mental decline. With aging, the liver becomes less efficient at metabolizing drugs, and the kidneys eliminate them from the body more slowly. As a result, drugs tend to accumulate in the body. Elderly people in poor health and those taking several different medications are especially vulnerable.”
The guide continued with a list of the possible classes of prescription drugs that number in the hundreds:
“The list of drugs that can cause dementia-like symptoms is long. It includes antidepressants, antihistamines, anti-Parkinson drugs, anti-anxiety medications, cardiovascular drugs, anticonvulsants, corticosteroids, narcotics, sedatives.”
The Harvard guide went on to emphasize that Alzheimer’s can only be accurately diagnosed on a post-mortem examination. The guide states that “Alzheimer’s is distinguished from other dementias at autopsy by the presence of sticky beta-amyloid plaques outside brain cells (neurons) and fibrillary tangles within neurons (all indicative of cellular death). Although such lesions may be present in any aging brain, in people with Alzheimer’s these lesions tend to be more numerous and accumulate in areas of the brain involved in learning and memory.”
“The leading theory is that the damage to the brain results from inflammation and other biological changes that cause synaptic loss and malfunction, disrupting communication between brain cells. Eventually the brain cells die, causing tissue loss In imaging scans, brain shrinkage is usually first noticeable in the hippocampus, which plays a central role in memory function.”
But even the Harvard guide inexplicably failed to mention known mitochondrial toxins such as statin drugs, metformin, Depakote, general anesthetics, fluoroquinolone antibiotics, fluorinated psychotropic drugs, NutraSweet (every molecule of aspartame, when it reaches 86 degrees F, releases one molecule of the excitotoxin aspartic acid and one molecule of methanol [wood alcohol] which metabolizes into the known mitochondrial poison formaldehyde [embalming fluid]), pesticides (including the chlorinated artificial sweetener Splenda, which was initially developed as a pesticide) or the mercury (thimerosal), aluminum and formaldehyde which are common ingredients in vaccines. These are only some of the synthetic drugs that are capable of causing mitochondrial damage in brain cells – with memory loss, confusion and cognitive dysfunction, all early symptoms of dementia.
It is tragic, but all–too-common, for reversible and preventable drug-induced dementias (therefore of known cause and thus not Alzheimer’s) to be mis-diagnosed as Alzheimer’s disease “of unknown etiology” and to then be prescribed costly, essentially ineffective and potentially toxic drugs – whose mitochondrial toxicities have not been tested for.
(The pharmaceutical industry, it should be noted, is not required by the FDA to test its drugs for mitochondrial toxicity when it is doing its studies for marketing approval, again exhibiting the total disdain for the Precautionary Principle by both industry and the regulatory agencies such as the FDA, the CDC and WHO.)
There is much more in the basic neuroscience literature proving the connections, at least from authors who do not have conflicts of interest with BigPharma and BigMedicine. The authors of these articles have raised the questions and have published the proof that concerned families of patients and their physicians desperately need to know.
Don’t expect BigPharma to respond or to offer apologies or mea culpas. Do expect denials, dismissals, distractions, discrediting and then the delaying of real legitimate explorations of the real scientific evidence that exposes its subterfuge in the name of maintaining large profits for their stakeholders.
Here are the abstracts from just two of the many peer-reviewed articles from various science journals that support the thesis of this column.
Medication-induced mitochondrial damage and disease
Published in the Molecular Nutrition and Food Research journal ; 2008 Jul;52(7):780-8.
Authors: Neustadt, J, Pieczenik SR.
Abstract
Mitochondrial Dysfunction and Psychiatric Disorders
From: The Journal of Neurochemical Research 2009 Jun;34(6):1021-9.
Abstract
Mitochondrial oxidative phosphorylation is the major ATP-producing pathway, which supplies more than 95% of the total energy requirement in the cells. Damage to the mitochondrial electron transport chain has been suggested to be an important factor in the pathogenesis of a range of psychiatric disorders. Tissues with high energy demands, such as the brain, contain a large number of mitochondria, being therefore more susceptible to reduction of the aerobic metabolism. Mitochondrial dysfunction results from alterations in biochemical cascade and the damage to the mitochondrial electron transport chain has been suggested to be an important factor in the pathogenesis of a range of (so-called) neuropsychiatric disorders, such as (psychotropic drug-treated) bipolar disorder, depression and schizophrenia….Alterations of mitochondrial oxidative phosphorylation in (anti-psychotic drug-treated) schizophrenia have been reported in several brain regions and also in platelets. Abnormal mitochondrial morphology, size and density have all been reported in the brains of (anti-psychotic drug-treated) schizophrenic individuals. Considering that several studies link energy impairment to neuronal death, neurodegeneration and disease, this review article discusses energy impairment as a mechanism underlying the pathophysiology of some psychiatric disorders, like (psychotropic drug-treated) bipolar disorder, depression and schizophrenia.
Dr Kohls is a retired physician who practiced holistic mental health care for the last decade of his career, and took seriously the Hippocratic Oath that he swore when he received his medical degree. He is also a peace and justice advocate and writes a weekly column for the Reader Weekly, an alternative newsweekly published in Duluth, Minnesota, USA. The last three years of Dr Kohls’ columns are archived at http://duluthreader.com/articles/categories/200_Duty_to_Warn.
Recent Academy of Sciences Reports on Climate Change were Partially Funded by CIA
By Noel Brinkerhoff | AllGov | February 17, 2015
A voluminous scientific study on climate change and man-made possibilities of altering it was funded by several federal agencies, including the Central Intelligence Agency (CIA).
The CIA’s decision to partially fund the research left at least one expert who participated in the study a little uneasy.
Scientist Alan Robock at Rutgers University told The Guardian the CIA’s investment in the $630,000 study “makes me really worried who is going to be in control” of efforts to stem the impact of climate change.
In addition to the CIA, the National Aeronautics and Space Administration, the Department of Energy, and the National Oceanic and Atmospheric Administration funded the National Academy of Sciences research that produced two reports within the study.
One report addressed ways to remove carbon dioxide from the atmosphere, and the other looked at ways to alter cloud cover or change the planet’s surface to make it reflect more sunlight back into space.
The CIA never explained to the academy why it was funding the project.
But Robock became suspicious after two CIA consultants contacted him inquiring about the possibility of another country gaining control of the weather.
“They said: ‘We are working for the CIA and we’d like to know if some other country was controlling our climate, would we be able to detect it?’ I think they were also thinking in the back of their minds: ‘If we wanted to control somebody else’s climate could they detect it?’” he told The Guardian.
He said that he told the consultants that any attempt to generate large, climate-changing clouds would be noticed by weather satellites or other equipment used to monitor the atmosphere.
The CIA didn’t respond to a press inquiry about its involvement and has previously refused to confirm its role in the study. In 2013, CIA spokesman Edward Price told Mother Jones: “It’s natural that on a subject like climate change the Agency would work with scientists to better understand the phenomenon and its implications on national security.”
Using the weather as a weapon is forbidden under international law, per the Environmental Modification Convention of 1978.
The agency’s inquiry left Robock concerned. “I’d learned of lots of other things the CIA had done that didn’t follow the rules,” he said. “I thought that wasn’t how my tax money was spent.”
The CIA opened its own climate change office in 2009 but shut it down three years later after criticism from some Republicans who called it a distraction from the agency’s focus on combatting terrorism.
To Learn More:
Spy Agencies Fund Climate Research in Hunt for Weather Weapon, Scientist Fears (by Ian Sample, The Guardian )
CIA Backs $630,000 Scientific Study on Controlling Global Climate (by Dana Liebelson and Chris Mooney, Mother Jones )
C.I.A. Closes Its Climate Change Office (by John Broder, New York Times )
Climate “Science”: Consensus or Conformity?
An Indictment
By David Small | Climate Etc. | February 15, 2015
I started a PhD program in Environmental Engineering because I worried about climate change. It didn’t take long for me to become a skeptic.
My first paper, a study about precipitation intensity over the U.S., was rejected by reviewers because it contradicted the climate model projections. Though they could find nothing wrong with the methodology, they decided observational data must be flawed because climate models couldn’t possibly be wrong and wrote that the paper could not be published.
I then started reading the atmospheric science literature about precipitation trends. It was clear to me that the theory about changes in precipitation intensity were designed to explain climate model results that didn’t mesh with observations. When I found that changes in observed precipitation were largest in autumn, and did not find the same patterns of precipitation in climate models outputs, I really became skeptical about the use of climate models. When I started working with climate models and saw how poorly they reproduce precipitation patterns, I was forced into the realization that the “science” was being fit to the models and that the models were not very realistic. From my perspective, this runs contrary to the scientific method.
After finishing my PhD in Environmental Engineering, I earned a M.S. in Atmospheric Science and started working on a PhD. As I learned more about meteorology and atmospheric dynamics, I started to see the contradictions in the climate change discussion.
I had another paper refused by a high profile journal because it showed that cold air is required to produce the conditions that cause storm surges in the western Canadian arctic. That suggestion really seemed to upset the editor (an engineer) who wouldn’t even send it out for review. My later research has shown the importance of strong jets and cold air in building the blocking ridges that cause the extreme weather we’ve seen over the last two autumns/winters. The claims that are being made that a warming of the arctic will lead to warmer conditions in the mid-latitudes because it will cause more blocking are preposterous because strong jets are needed to support the blocking ridges. I received dozens of letters saying my published paper must be wrong because I suggest that strong jets, not weak jets, cause blocking. Most of the claims being made by climate change advocates appear to run contrary to basic meteorology.
As I’ve been attacked personally and professionally for offering contrary views, I decided to leave the field. I will defend my Atmospheric Science PhD thesis and walk away. It’s become clear to me that it is not possible to undertake independent research in any area that touches upon climate change if you have to make your living as a professional scientist on government grant money or have to rely on getting tenure at a university. The massive group think that I have encountered on this topic has cost me my career, many colleagues and has damaged my reputation among the few people I know in the field.
I’m leaving to work in the financial industry. It’s a sad day when you feel that you have to leave a field that you are passionately interested in because you fear that you won’t be able to find a job once your views become widely known. Until free thought is allowed in the climate sciences, I will consider myself a skeptic of catastrophic human induced global warming.





